MNTF differentiation and growth of stem cells

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专利权人:

ジェナボン バイオファーマシューティカルズ エルエルシー

发明人:

ディーパ・エム・デシュパンデ,ダグラス・エイ・カー,プイ－ユク・ドロシー・コ,プイ-ユク・ドロシー・コ

申请号：

JP2008540231

公开号：

JP5270362B2

申请日:

2006.11.10

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

The present invention provides methods for inducing differentiation of an embryonic stem cell into a motor neuron using a motoneuronotrophic factor (MNTF) or its peptide analogs. The present invention further provides a method for isolating a population of stem cell derived motor neurons and a population of cells comprising the differentiated neural cells. Additionally, the present invention is directed to a method of enhancing the survival of the differentiated neural cells in long term cell cultures. Finally, the present invention provides compositions containing MNTF or its peptide analogs for therapeutic use in conjunction with stem cells.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/