A biopsy assembly for collecting tissue samples by means of a biopsy needle when introduced in a body cavity. The biopsy assembly comprises an elongated member (101), with a longitudinal axis (102), configured with: a first needle guide (203), arranged to guide a needle in a direction transverse to the longitudinal axis (102), and a second needle guide (204, 303) arranged to guide a needle in a direction along the elongated member (101).