PAGES SANTACANA LLUIS MIQUEL,EASTWOOD PAUL ROBERT,BACH TAÑA JORDI
申请号：
NZ61890412
公开号：
NZ618904A
申请日:
2012.07.23
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Provided are pyridin-2(1H)-one derivative compounds of the general formula (I), wherein the variables are as defined in the specification. Examples of the compounds include (5)-3-(4-( 1-( 5-fluoropyridin-2-yl)ethylamino)pyrimidin-2-ylamino)pyridin-2(1H)-one and 3-(5-{ 6-{ [(1S)-1-(5-Fluoropyridin-2-yl)ethyl]amino} -2-[(2-oxo-1,2-dihydropyridin-3-yl)amino]pyrimidin-4-yl} -1,3-thiazol-2-yl)benzoic acid. The compounds are JAK inhibitors. The compounds may be useful in the treatment of cancers and immunological and inflammatory diseases.
