CONSTRUCTIONS CONTENANT LE FACTEUR 15 DE DIFFÉRENTIATION DE CROISSANCE (GDF-15)

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专利权人:

Amgen Inc.

发明人:

申请号：

EP14752711.3

公开号：

EP3027642B1

申请日:

2014.07.31

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

Constructs comprising GDF15, and mutants thereof are provided. In various embodiments the constructs comprising GDF15, and mutants thereof, can be of use in the treatment or ameliorating a metabolic disorder. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy.

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