HAN CHEOL KYU,AUH JIN,CHOI NAM SONG,HAN CHANG KYUN,KIM TAE JEONG,PAE KAMSA,SHIN YOUNG JUNE,HAN DONG OH,AHN SOON KIL
申请号：
IN2622/MUMNP/2014
公开号：
IN300444B
申请日:
2013.06.04
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
The present invention relates to a novel compound or a pharmaceutically acceptable salt thereof inhibiting 11²-HSD1 enzyme activity, a preparation method of the same, and a pharmaceutical composition comprising the same as an active ingredient. Since the compound of the present invention selectively inhibits the activity of 11²-HSD1 (11²-Hydroxysteroid dehydrogenase type 1), the compound of the invention can be effectively used as a therapeutic agent for the treatment of diseases caused by the over-activation of 11²-HSD1 such as non-insulin dependent type II diabetes, insulin resistance, obesity, lipid disorder, metabolic syndrome, and other diseases or condition mediated by the excessive activity of glucocorticoid. EP2865664A1
