INC.;THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;YUMA THERAPEUTICS, INC.;YUMA THERAPEUTICS
发明人:
CUNY, GREGORY D.,GLICKSMAN, MARCIE A.,HODGETTS, KEVIN J.,MATHIEU, STEVEN L.,PERRELLA, YUKARI Y.,DARMENCY, VINCENT,LUSIC, HRVOJE
申请号:
CA2952230
公开号:
CA2952230A1
申请日:
2015.06.15
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention relates to 2-amino-4-arylpyrimidine and 2-amino-4-aryltriazine compounds as inhibitors of heat shock protein 90 family of chaperone proteins. The invention also features pharmaceutical compositions and kits that include the compounds and compositions of the invention. The invention further relates to the medical use of these compounds and compositions for the treatment of a disorder in a subject. For example, the disorder is a neurodegenerative disease.