Sheth, Urvi,Fanning, Tev T.D.,Numa, Mehdi,Binch, Hayley,Hurley, Dennis James,Zhou, Jinglan,Hadida Ruah, Sara S.,Hazlewood, Anna R.,Silina, Alina,Vairagoundar, Rajendran,Van Goor, Fredrick F.,Grootenhu
申请号:
AU2010327993
公开号:
AU2010327993A1
申请日:
2010.12.10
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention relates to 4 -oxo- lH-quinoline- 3 carboxamides as modulators of ATP -Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present Invention also relates to methods of treating ABC transporter mediated diseases using such modulators.