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flibanserine formulations and method for their manufacture.
专利权人:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
发明人:
WOLFRAM EISENREICH,THOMAS FRIEDL,FLORIAN SOMMER,NANTHARAT PEARNCHOB,KARL GERHARD WAGNER
申请号:
BRPI0716439
公开号:
BRPI0716439A2
申请日:
2007.08.10
申请国别(地区):
BR
年份:
2013
代理人:
摘要:
The present invention provides pharmaceutical release systems comprising an therapeutically effective amount of flibanserin and at least one pharmaceutically acceptable excipient, characterized in that said pharmaceutical release systems exhibit a pharmacokinetic profile that is characterized by an average maximum flibanserin plasma concentration Cmax lower than 300 ng/mL, preferably lower than 200 ng/mL after administration of a single dose to healthy volunteers in fasted state or directly after a meal.
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