Theodore J. Lampidis,Metin Kurtoglu,Johnathan C. Maher
申请号：
US12280541
公开号：
US08242167B2
申请日:
2007.02.26
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A method for treating cancer by killing selected tumor cells such as human breast, non-small cell lung cancer cells, pancreatic cancer cells, osteosarcoma cancer cells, and glioblastoma cells, includes administering to a patient in need of treatment, an effective amount of at least one mannose analog such as 2-DG or 2-FM or 2-CM. The killing is believed to be due to an interference with glycosylation. A theranostic method includes determining whether a patient. cancer tumor sample comprises cells sensitive to killing to at least one mannose analog due to an interference with glycosylation.
