Cylodextrin Complexation Methods for Formulating Peptide Proteasome Inhibitors

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专利权人:

Sean Dalziel;Evan Lewis;Mouhannad Jumaa;Peter Shwonek

发明人:

Evan Lewis,Peter Shwonek,Sean Dalziel,Mouhannad Jumaa

申请号：

US13614599

公开号：

US20130303465A1

申请日:

2012.09.13

申请国别(地区):

US

年份:

2013

代理人:

摘要：

This disclosure provides methods for formulating compositions comprising one or more peptide proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin. Such methods substantially increase the solubility and stability of these proteasome inhibitors and facilitate both their manufacture and administration.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/