Judi Charlotte Neuss;Joanna Rachel Quincey;Mezher Hussein Ali;Daniel Christopher Brookings;Daniel James Ford;Jackalyn Hinkins;Andrew Harry Parton;Richard Jeremy Franklin;Julien Alistair Brown
发明人:
Andrew Harry Parton,Mezher Hussein Ali,Daniel Christopher Brookings,Julien Alistair Brown,Daniel James Ford,Richard Jeremy Franklin,Barry John Langham,Judi Charlotte Neuss,Joanna Rachel Quincey
申请号：
US13821294
公开号：
US09029392B2
申请日:
2011.09.02
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Disclosed are a series of quinoline and quinoxaline derivatives comprising a fluorinated ethyl side-chain, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions. The compounds are of general formula (I):
