Use of allopregnanolone in a cylodextrin carrier in the manufacture of a medicament for treating traumatic brain injury in an individual in need thereof for treatment of a central nervous system injury and for treating a CNS disorder in a subject. Further, a pharmaceutical dosage unit comprising a complex of an alloprenanolone and a cylodextrin. In one example, the cyclodextrin is sulfobutylether-beta-cyclodextrin.
