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LIVER DELIVERY-BASED ANTIVIRAL PRECURSOR DRUG NUCLEOSIDE CYCLOPHOSPHATE COMPOUND AND USE THEREOF
专利权人:
ZHEJIANG PALOALTO PHARMACEUTICAL TECHNOLOGY CO LTD
发明人:
XI, Zhijian,XU, Huaqiang,LU, Chunping,WU, Zhongshan,SUN, Feng,ZHANG, Zhenwei
申请号:
PH12018502735
公开号:
PH12018502735A1
申请日:
2018.12.21
申请国别(地区):
PH
年份:
2019
代理人:
摘要:
Provided are an antiviral precursor drug nucleoside cyclophosphate compound based on liver specific delivery (LSD) technology and a use thereof, and in particular, provided are a compound of formula II and an isomer, pharmaceutically acceptable salt, hydrate, and solvate thereof, and the corresponding pharmaceutical composition. Also provided are the use of the compounds alone or in combination with other antiviral drugs in the treatment of hepatitis B virus (HBV), hepatitis D virus (HDV) and human immunodeficiency virus (HIV) and diseases caused by same.
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中国工程科技知识中心
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