The invention is directed to a drug delivery device (1) comprising a primary drug delivery assembly (3) for the delivery of a primary medicament with a primary dose setting mechanism (8) and a secondary drug delivery assembly (4) for the delivery of a secondary medicament. A selection element (13) is movable in a first and a second direction and configured such that movement of the selection element (13) in the first direction and in the second direction causes the setting of an increasing dose in the primary dose setting mechanism (8).