Kevin McGee,Scott Zook,Andrew Carr,Thierry Bonnaud
申请号:
US15338214
公开号:
US10065952B2
申请日:
2016.10.28
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided herein are salts of (S)-2-amino-3-methyl-butyric acid (2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl ester in amorphous and crystalline forms, and processes of preparation, and pharmaceutical compositions thereof. Also provided are methods of their use for treating, preventing, or ameliorating one or more symptoms of neurological disorders and diseases including hyperkinetic movement disorders or diseases.