БЕНДЖАМИН Дон (CH),КОЛОМБИ Марко (CH),ХАЛЛЬ Михаэль (CH),МОРОНИ Кристоф (CH)
申请号：
RU2013137380/15
公开号：
RU2013137380A
申请日:
2012.01.09
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
1. A pharmaceutical composition comprising sirosingopin and mitochondrial ingibitor.2. A pharmaceutical composition according to claim 1, comprising sirosingopin and metformin or fenformin.3. A pharmaceutical composition according to claim 1, comprising sirosingopin and metformin.4. A pharmaceutical composition according to claim 1, comprising sirosingopin and mitochondrial inhibitor selected from rotenone, pieritsidina A, epiberberina, 2-thenoyltrifluoroacetone (TTFA), antimycin A, oligomycin, carbonyl cyanide-p-triftormetoksifenilgidrazona (FCCP) and stavudina.5. A pharmaceutical composition according to claim 1, comprising sirosingopin and oligomitsin.6. Pharmaceutical composition according to one of claims 1-5, wherein the ratio of the amounts (wt. / Wt.) Sirosingopina and mitochondrial inhibitor is from 1 to 10 to 1 to 1000.7. A pharmaceutical composition according to claim 3, wherein the ratio of the amounts (wt. / Wt.) Sirosingopina and metformin is from 1 to 10 to 1 to 200.8. A pharmaceutical composition according to claim 5, wherein the ratio of the amounts (wt. / Wt.) And oligomycin sirosingopina is from 1000: 1 to 10,000 to 1.9. Combination sirosingopina and mitochondrial inhibitor for use in treating cancer or autoimmune zabolevaniy.10. A combination according to claim 9, wherein the mitochondrial inhibitor is metformin.11. A combination according to claim 9, wherein the mitochondrial inhibitor is oligomitsin.12. Combination sirosingopina and mitochondrial inhibitor of claim 9 for use in the treatment of carcinoma, sarcoma, leukemia, myeloma, lymphoma, and any type of nervous sistemy.13 cancer. Combination sirosingopina and mitochondrial inhibitor of claim 9 for use in immunosuppressive terapii.14. Combination sirosing1. Фармацевтическая композиция, содержащая сиросингопин и митохондриальный ингибитор.2. Фармацевтическая композиция по п.1, содержащая сиросингопин и метформин или фенформин.3. Фармацевтическая композиция по п.1, содержащая сиросингопин и м
