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Antisense Modulation of Apolipoprotein B Expression
- 专利权人:
- Genzyme Corporation
- 发明人:
- Geary, Richard S.,Yu, Zhengrong,Crooke, Rosanne M.
- 申请号:
- AU2014233601
- 公开号:
- AU2014233601A1
- 申请日:
- 2014.09.25
- 申请国别(地区):
- AU
- 年份:
- 2014
- 代理人:
- 摘要:
- #$%^&*AU2014233601A120141016.pdf#####ABSTRACT Methods for the rapid and long-term lowering of lipid levels in human subjects and for the treatment of conditions associated with elevated LDL-cholesterol and elevated apolipoprotein B are provided.WO 2006/020676 PCT/US2005/028342 Figure 1 2 14 MAD25 MD25 MD25 APOB-1 00 LDL T,,tal CholesterolI p= 0.0002 p= 0.0002 p< 0.0001 0 20~ 0 0 0 0 2O o0 0 0 0 0 0 0 0 0 0. O 00 0O 0 0 0 0 0 0 a)0 0 -0 00 0 C 0 0 0 0 0 O0 06 0 -00 -100 00 0 2 14 2 14 Trough AUC (pg*hr/mL) 1/1
- 来源网站:
- 中国工程科技知识中心
- 来源网址:
- http://www.ckcest.cn/home/