Общество с ограниченной ответственностью "Изварино Фарма" (RU)
发明人:
Хазанова Елена Сергеевна (RU),Ногай Сергей Юрьевич (RU),Филиппова Евгения Александровна (RU)
申请号：
RU2018140201
公开号：
RU2018140201A
申请日:
2018.11.14
申请国别(地区):
RU
年份:
2020
代理人:
摘要：
FIELD: medicine； pharmaceuticals.SUBSTANCE: group of inventions relates to pharmaceutics, specifically to an extrudate of a mixture of sodium mycophenolate, polyvinylpyrrolidone and polyethylene glycol for making an oral solid dosage form, which is obtained at extrusion temperature of 60–140 °C, wherein sodium mycophenolate is in crystalline form； use of said extrudate for preparing an oral solid dosage form and an oral solid dosage form having an immunosuppressive action containing said extrudate.EFFECT: group of inventions ensures preservation of crystallinity of sodium mycophenolate after extrusion.5 cl, 3 dwg, 1 tbl, 24 ex
