BAXTER INTERNATIONAL INC.;BAXTER HEALTHCARE SA;ARRIVA PHARMACEUTICALS, INC.
发明人:
KUMAR, HARISH,KREIGER, TIMOTHY,KABINGUE, KEN,MOSHER, VIRGINIA,BARR, PHILIP J.,BATHURST, IAN C.,DURRANI, MANZER J.
申请号:
DK04811377
公开号:
DK1684719T3
申请日:
2004.11.11
申请国别(地区):
DK
年份:
2012
代理人:
摘要:
Alpha 1-antitrypsin compositions and treatment methods using such compositions for treating a variety of pulmonary diseases are provided. The compositions generally contain AAT, a stabilizing carbohydrate such as trehalose, a surfactant such as Polysorbate 80 and an antioxidant to stabilize AAT for use as a therapeutic. The formulations can be prepared as both liquids and solids and administered by nebulization of the liquid formulation or by conversion of dry powder formulation into an aerosol.