A protection apparatus (10) for washing endoscopic medical instruments (12), such as transesophageal probes or suchlike, having a tubular part to be subjected to washing which at one end has electronic components to be protected, comprises a watertight box-like body (14) that delimits internally a housing compartment (15) to position, through an aperture (22), the electronic components of the instrument (12) in a protected condition from the outside.