Chen, Jianhe,Lau, Jesper F.,Kodra, János Tibor,Wieczorek, Birgit,Linderoth, Lars,Thøgersen, Henning,Rasmussen, Salka Elbøl,Garibay, Patrick William
申请号：
AU2017207862
公开号：
AU2017207862A1
申请日:
2017.01.13
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The invention relates to compounds derived from the EGF(A) domain of LDL-R, in particular compounds comprising a peptide analogue of the wild-type EGF(A) (LDL-R(293- 332)) sequence and at least one substituent comprising at least one fatty acid group. The invention also relates to a pharmaceutical composition thereof and use a medicament. The novel EGF(A) compounds of the invention are useful as treatment e.g. in the field of cholesterol lowering, dyslipidaemia and cardiovascular disease.
