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[4-(6-halo-7-substituted-2,4-dioxo-1,4-dihydro-2h-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylureas and forms and methods related thereto
专利权人:
Portola Pharmaceuticals; Inc.
发明人:
Grant, Craig M.,Zhang, Xiaoming,Cannon, Hilary,Mehrotra, Mukund,Huang, Wolin,Scarborough, Robert M.
申请号:
AU2006311795
公开号:
AU2006311795B2
申请日:
2006.11.03
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention provides novel sulfonylurea compounds of formula (I) andpharmaceutically acceptable derivatives and polymorph and amorphous forms thereof.The compounds in their various forms are effective platelet ADP receptor inhibitorsand may be used in various pharmaceutical compositions, and are particularly effectivefor the prevention and/or treatment of cardiovascular diseases, particularlythose diseases related to thrombosis. The invention also provides a method forpreparing such compounds and forms and for preventing or treating thrombosisand thrombosis related conditions in a mammal comprising the step of administeringa therapeutically effective amount of a compound of formula (I) or a pharmaceuticallyacceptable salt or forms thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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