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[4-(5-aminometylo-2-fluorofenylo)piperydyn-1-ylo]-[7-fluoro-1-(2-metoksyetylo)-4-trifluorometoksy-1H-indol-3-ilo]metanon jako inhibitor tryptazy komórek tucznych
专利权人:
SANOFI
发明人:
CHOI-SLEDESKI, YONG MI,CHOY, NAKYEN,POLI, GREGORY BERNARD,SHAY, JOHN J. JR.,SHUM, PATRICK WAI-KWOK,SLEDESKI, ADAM W.
申请号:
PL09791693
公开号:
PL2367812T3
申请日:
2009.08.20
申请国别(地区):
PL
年份:
2016
代理人:
摘要:
The present invention is directed to an indole benzylamine compound of formula I: useful as an inhibitor of tryptase. In addition, the present invention is directed to the use of the compound for treating a patient suffering from, or subject to, a physiological condition in need of amelioration by inhibition of tryptase, comprising administering to the patient of a therapeutically effective amount of the compound, and to a pharmaceutical composition comprising a pharmaceutically effective amount of the compound of formula I, and a pharmaceutically acceptable carrier.
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