FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG
发明人:
KRUSE, CHARLI
申请号：
EP10011672.2
公开号：
EP2446892A3
申请日:
2004.04.08
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
Die Erfindung betrifft isolierte pluripotente adulte Stammzellen, welche aus exokrinem Drüsengewebe erhalten wurden, sowie Verfahren zur Isolierung und Kultivierung dieser pluripotenten Stammzellen.Isolated, pluripotent adult stem cells (A) obtained from exocrine gland tissue, is new. Independent claims are also included for: (1) stem cell cultures that comprise (A) in a culture medium that allows stable maintenance and replication of the cells without significant differentiation (2) primary stem cell cultures of exocrine gland tissue in which most of the living cells are undifferentiated (A) (3) organoid bodies (OB) obtained by culturing (A) under spatial conditions that provide three-dimensional contact between cells (4) secondary organoid bodies (OB2) produced from OB by spontaneous growth on surfaces without confined surface adhesion (5) preparing (A) (6) preparing differentiated cells from (A) (7) differentiated cells (B) obtained from (A) and (8) differentiation culture comprising (B) and/or OB or OB2 in a differentiation medium. ACTIVITY : Immunostimulant Cytostatic Hepatotropic Cardiant Neuroprotective Immunosuppressive Antianemic Antidiabetic Antiinflammatory Antibacterial. No biological data given. MECHANISM OF ACTION : Gene Therapy Tissue Replacement.
