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Process for the Preparation of Gadobenate Dimeglumine Complex in a Solid Form
专利权人:
BRACCO IMAGING S.p.A.
发明人:
Pier Lucio ANELLI,Pierfrancesco MOROSINI,Silvia CERAGIOLI,Fulvio UGGERI,Luciano LATTUADA,Roberta FRETTA,Aurelia FERRIGATO
申请号:
US15130160
公开号:
US20160228583A1
申请日:
2016.04.15
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention discloses a process for the preparation of gadobenate dimeglumine complex in a solid form. In particular, said solid form is conveniently obtained by spray-drying a corresponding liquid suspension at a given temperature and concentration. The present invention is particularly advantageous for the industrial scale as the solid form may be obtained by employing water as a solvent, which is a non-toxic solvent, easy to handle and basically not requiring troublesome health or safety precautions.
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