Pier Lucio ANELLI,Pierfrancesco MOROSINI,Silvia CERAGIOLI,Fulvio UGGERI,Luciano LATTUADA,Roberta FRETTA,Aurelia FERRIGATO
申请号:
US15130160
公开号:
US20160228583A1
申请日:
2016.04.15
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention discloses a process for the preparation of gadobenate dimeglumine complex in a solid form. In particular, said solid form is conveniently obtained by spray-drying a corresponding liquid suspension at a given temperature and concentration. The present invention is particularly advantageous for the industrial scale as the solid form may be obtained by employing water as a solvent, which is a non-toxic solvent, easy to handle and basically not requiring troublesome health or safety precautions.