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Metallo-β-lactamase inhibitors
专利权人:
Ken Chikauchi;Yukiko Hiraiwa;Mizuyo Ida;Akihiro Morinaka;Toshiaki Kudo;Takao Abe
发明人:
Ken Chikauchi,Mizuyo Ida,Takao Abe,Yukiko Hiraiwa,Akihiro Morinaka,Toshiaki Kudo
申请号:
US11889296
公开号:
US08093294B2
申请日:
2007.08.10
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A new metallo-β-lactamase inhibitor which acts as a medicament for inhibiting the inactivation of β-lactam antibiotics and recovering anti-bacterial activities is disclosed. The maleic acid derivatives having the general formula (I) have metallo-β-lactamase inhibiting activities. It is possible to recover the anti-bacterial activities of β-lactam antibiotics against metallo-β-lactamase producing bacteria by combining the compound of the general formula (I) with β-lactam antibiotics.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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