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RADIOLABELLING
专利权人:
Christian PRENANT
发明人:
Christian PRENANT
申请号:
US13447030
公开号:
US20120288445A1
申请日:
2012.04.13
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Compounds of the formula (I) are disclosed:18F—(CHR)n(CH2)mCHO  (I)in which n and m are independently 0 and 1 with at least one of n and m being 1, and R (if present) is a hydrogen atom or a methyl group, subject to the proviso that if n is 1 and R is methyl then m is 0. Synthesis of the compounds is described together with their use in radiolabelling reactions, e.g. for the radiolabelling of peptides to facilitate detection by Positron Emission Tomography (PET) imaging.The preferred compound is [18F]Fluoroacetaldehyde.
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