Jari Ratilainen;Olli Törmäkangas;Arja Karjalainen;Paavo Huhtala
发明人:
Jari Ratilainen,Olli Törmäkangas,Arja Karjalainen,Paavo Huhtala
申请号：
US12280026
公开号：
US08501814B2
申请日:
2007.03.02
申请国别(地区):
US
年份:
2013
代理人:
摘要：
A compound of formula (I), an isomer, metabolite, or a pharmaceutically acceptable salt or ester thereof is disclosed. Compounds of the invention possess utility as a tissue-selective androgen receptor modulators (SARM) and are useful in hormonal therapy, e.g. in the treatment or prevention of hypogonadism, muscle wasting, osteoporosis, benign prostate hyperplasia, obesity associated with a metabolic syndrome, male and female sexual dysfunction and reduced libido, and androgen decline in aging male or female.
