Esben Peter Friis;Tomoko Matsui;Leonardo De Maria;Soeren Flensted Lassen;Lars Kobberoee Skov;Allan Noergaard;Jesper Vind
发明人:
Soeren Flensted Lassen,Leonardo De Maria,Lars Kobberoee Skov,Esben Peter Friis,Tomoko Matsui,Allan Noergaard,Jesper Vind
申请号：
US13472822
公开号：
US08507240B2
申请日:
2012.05.16
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to phytases having at least 76% identity to a phytase derived from Hafnia alvei and comprises at least one modification in the amino acid sequence thereof. These phytase variants have modified, preferably improved, properties, such as, reduced protease sensibility, preferably they exhibit improved properties in respect of thermal performance, such as heat-stability (temperature stability, thermostability), steam stability, pelleting stability and/or temperature profile； and/or protease stability, in particular pepsin stability, pH profile, specific activity, substrate specificity, performance in animal feed (such as an improved release and/or degradation of phytate), susceptibility to glycation, and/or glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.
