Robert James Domett Nairne,Andrew John Healey,Edvin Wilhelm Johannesen
申请号:
US12671076
公开号:
US08431111B2
申请日:
2008.07.29
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to labelled cMet binding peptides suitable for optical imaging in vivo. The peptides are labelled with a benzopyrylium dye suitable for imaging in the red to near-infrared region. Also disclosed are pharmaceutical compositions and kits, as well as in vivo imaging methods, especially of use in the detection, staging, diagnosis, monitoring of disease progression or monitoring of treatment of colorectal cancer (CRC).