The present invention relates to a Chinese herbal medicine composition, Chinese herbal preparation and preparation method and application of the same. The present invention belongs to Chinese herbal preparation technical field. The Chinese herbal medicine composition is composed of active pharmaceutical ingredient, vinegary corydalis, panax notoginseng, paeonia veitchii lynch, salvia miltiorrhiza, chuanxiong, carthami flos, caesalpinia sappan and caulis spatholobi. The Chinese herbal preparation includes active ingredients and pharmacologically acceptable carriers. The Chinese herbal medicine composition and Chinese herbal preparation according to the present invention may be able to suppress or delay the apoptosis of pancreatic beta-cells, and enhance the restoration of functions of pancreatic beta-cell.本發明涉及一種中藥組合物、中藥製劑及其製備方法與用途,屬於中藥製劑技術領域。所述中藥組合物由原料藥黃芪、醋製延胡索、三七、赤芍、丹參、川芎、紅花、蘇木和雞血藤製成;所述中藥製劑包括活性成份和藥學上可接受的載體。本發明的中藥組合物和中藥製劑具有能夠抑制或延緩胰島β細胞凋亡、促進胰島β細胞功能恢復的作用。