SON, JUNG BEOM,손정범,KIM, NAM DU,김남두,CHANG, YOUNG KIL,장영길,KIM, HEE CHEOL,김희철,KIM, JI SOOK,김지숙,JUNG, YOUNG HEE,정영희
申请号：
KR1020110146537
公开号：
KR1020120079015A
申请日:
2011.12.29
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A novel bicyclic compound for controlling G protein-coupled receptors is provided to treat or prevent diseases associated with the receptor control. CONSTITUTION: A bicyclic compound is denoted by chemical formula 1. A pharmaceutical composition for preventing or treating diseases caused by G protein-coupled receptor control contains the compound of chemical formula 1 as an active ingredient. The G protein-coupled receptor is a GPR119G protein-coupled receptor. The diseases include diabetes, hyperglycemia, injured glucose resistance, insulin resistance, hyperinsulinemia, retinopathy, neuropathy, nephropathy, delayed wound healing, and atherosclerosis.본 발명은 G 단백질-커플링된 수용체의 조절을 위한 신규한 비사이클릭 화합물에 관한 것으로, 본 발명의 신규 화합물은 G 단백질-커플링된 수용체, 특히 GPR119 G 단백질-커플링된 수용체의 조절과 관련된 질환을 치료하거나 예방하는 효과를 제공한다.
