PROBLEM TO BE SOLVED: To provide a raw solution treatment apparatus and an operation method of the raw solution treatment apparatus capable of shortening a treatment time of a raw solution extracted from the body of a patient and improving operability of an operator.SOLUTION: The device for concentrating a raw solution to form a concentrated solution comprises a filter 10, a concentrator 20, a raw solution supply part, a supply solution passage, a filtrate supply passage, a concentrated solution passage, a waste solution passage, a solution feed part, and a control part for controlling an operation of the solution feed part so that a concentrated solution becomes a predetermined concentration ratio. The solution feed part includes a solution supply passage solution feed part provided at the solution supply passage, and a concentrated solution passage solution feed part provided at the concentrated solution passage or a waste solution passage solution feed part provided at the waste solution passage. The control part controls the operation of each solution feed part on the basis of the differential pressure between the filter membranes of the filter and/or the differential pressure between the concentrator membranes of the concentrator.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2020,JPO&INPIT【課題】患者の体内から抜いた原液の処理時間を短くすることができ、作業者の作業性を向上できる原液処理装置および原液処理装置の操作方法を提供する。【解決手段】原液を濃縮して濃縮液を形成する装置であって、濾過器10と、濃縮器20と、原液供給部と、給液流路と、濾過液供給流路と、濃縮液流路と廃液流路と、送液部と、濃縮液が所定の濃縮割合となるように送液部の作動を制御する制御部と、を備えており、送液部が、給液流路に設けられた給液流路送液部と、濃縮液流路に設けられた濃縮液流路送液部または廃液流路に設けられた廃液流路送液部と、を有しており、制御部は、濾過器の濾過器膜間差圧および/または濃縮器の濃縮器膜間差圧に基づいて各送液部の作動を制御する。【選択図】図1