A medical air mattress has a mattress body, a lower bedspread and an upper bedspread. The mattress body is formed by multiple air cells substantially parallel arranged in a row forming an air cell row. The upper bedspread covers the mattress body and is securely connected to the lower bedspread. The mattress further comprises a pumping assembly with a pump and at least a pipeline connecting the pump with the air cells such that inflating and/or deflating of the air cells is controllable selectively.