ABSTRACTAn external patch containing diclofenac hydroxyethylpyrrolidine prepared by laminating an adhesive layer on a backing, wherein said adhesive layer ischaracterized by comprising 5-50% by weight of styrene.isoprene-styrene block copolymer, 20-50% by weight of a tackifier rein； 5-70% by weight of a softeningagent, and 0.5:20% by weight of one or more solfibilizers selected from N-methyl,22pyrrolidone, propylene glycol and dimethyl stilfoxide. as essentialingredients, and 0.5-20% by *eight of diclofenac hydroxyethylpyrrolidine as anactive ingredient. The patch has excellent ransdermal absorption, lessskin-irritation and excellent stability of the drug.
