PROBLEM TO BE SOLVED: To provide an ophthalmologic disease therapeutic agent and the like, containing a vascular endothelial growth factor (VEGF) receptor inhibitor or an epithelium growth factor (EGF) receptor inhibitor, in the form of nanoparticles.SOLUTION: The present invention provides an ophthalmologic disease therapeutic agent, containing a vascular endothelial growth factor (VEGF) receptor inhibitor or an epithelium growth factor (EGF) receptor inhibitor, having the nature of building up in the retral ocular tissue when systemically administered, in the form of nanoparticles.SELECTED DRAWING: None【課題】ナノ粒子の形態の血管内皮増殖因子(VEGF)受容体阻害剤または上皮成長因子(EGF)受容体阻害剤を含む、眼科疾患治療剤等を提供すること。【解決手段】ナノ粒子の形態の、全身投与した場合に後眼部組織に滞留する性質を有する血管内皮増殖因子(VEGF)受容体阻害剤または上皮成長因子(EGF)受容体阻害剤を含む、眼科疾患治療剤。【選択図】なし