Alasdair Stamps;Christian Rohlff;Jonathan Alexander Terrett
发明人:
Christian Rohlff,Alasdair Stamps,Jonathan Alexander Terrett
申请号:
US13823999
公开号:
US09228023B2
申请日:
2011.10.03
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention provides antibodies which bind to the extracellular domain of the Tyrosine-protein kinase transmembrane receptor ROR1. Nucleic acid molecules encoding the antibodies, expression vectors, host cells and methods for expressing the antibodies are also provided. The antibodies may be used for the treatment of cancer, including non-small cell lung carcinoma, B-cell chronic lymphocytic leukemia and colon cancer.