The present invention relates to compounds of formula I, formula II, formula III, formula IV, formula V, formula VI, formula VII and formula VIII or pharmaceutically acceptable polymorphs, solvates, enantiomers, stereoisomers thereof. It relates to isomers and hydrates. A pharmaceutical composition comprising an effective amount of a compound of formula I, formula II, formula III, formula IV, formula V, formula VI, formula VII and formula VIII, and a method for the treatment of mucositis, including oral administration, gargle, buccal It can be formulated for side administration, rectal administration, topical administration, transdermal administration, transmucosal administration, intravenous administration, oral solution, buccal mucosa layered tablet, parenteral administration, syrup or injection. Such compositions can be used for the treatment of oral and gastrointestinal mucositis, mucosal inflammation and oral infectious diseases. [Selection figure] None本発明は、式Ｉ、式ＩＩ、式ＩＩＩ、式ＩＶ、式Ｖ、式ＶＩ、式ＶＩＩ及び式ＶＩＩＩの化合物又はそれらの薬学的に許容可能な多形、溶媒和物、鏡像異性体、立体異性体及び水和物に関する。有効量の式Ｉ、式ＩＩ、式ＩＩＩ、式ＩＶ、式Ｖ、式ＶＩ、式ＶＩＩ及び式ＶＩＩＩの化合物を含む医薬組成物並びに粘膜炎の治療のための方法は、経口投与、含嗽、頬側投与、経直腸投与、局所投与、経皮投与、経粘膜投与、静脈内投与、経口溶液、頬粘膜層状錠剤、非経口投与、シロップ剤又は注射用に配合され得る。そのような組成物は、口腔及び胃腸の粘膜炎、粘膜炎症及び口腔感染性疾患の治療のために使用することができる。【選択図】なし
