#$%^&*AU2011101443A420120119.pdf#####Abstract An implantable cardiac resynchronization device with atrioventricular optimization to reduce ventricular premature beats in heart failure patients with central sleep apnea and Cheyne Stokes Breathing. The cardiac output is augmented by optimizing V-V timing, whereby the optimum cardiac output will be assumed by an optimum end tidal C02 value rather than by traditional optimization techniques. Device reprogramming is performed via a pacemaker telemetry head positioned on the subjects skin over their implanted device, to enable the parameters to be changed according to protocol.