Pharmaceutical compositions for the treatment of tumors are provided, which are renbatinib and (6S, 9aS) -N-benzyl-8-({6- [3- (4-ethylpiperazin-1-yl) azetidin-1- Yl] pyridin-2-yl} methyl) -6- (2-fluoro-4-hydroxybenzyl) -4,7-dioxo-2- (prop-2-en-1-yl) hexahydro- 2H-pyrazino [2,1-c] [1,2,4] triazine-1 (6H) -carboxamide in combination therapy.종양 치료용 약제학적 조성물이 제공되며, 이는 렌바티닙 및 (6S,9aS)-N-벤질-8-({6-[3-(4-에틸피페라진-1-일)아제티딘-1-일]피리딘-2-일}메틸)-6-(2-플루오로-4-하이드록시벤질)-4,7-디옥소-2-(프로프-2-엔-1-일)헥사하이드로-2H-피라지노[2,1-c][1,2,4]트리아진-1(6H)-카복사미드의 병용 치료법에 사용된다.
