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5-HT2C receptor agonists and compositions and methods of use
专利权人:
아레나 파마슈티칼스, 인크.
发明人:
렌, 앨버트 에스.,셈플, 그레엄,주, 시우웬,세이지, 칼턴 알.
申请号:
KR1020177033892
公开号:
KR1020170140317A
申请日:
2016.04.26
申请国别(地区):
KR
年份:
2017
代理人:
摘要:
In some embodiments, the compounds herein are provided. In some embodiments, weight management, satiety induction, and food intake reduction, and obesity, antipsychotic-induced weight gain, Type 2 diabetes, Frederick-Willi Syndrome, tobacco / nicotine dependence, drug addiction, alcoholism, (Including insomnia, segmental sleep structures, and sleep disorders), urinary incontinence, mental disorders (including psychotic disorders), obsessive-compulsive disorder and impulse control disorders (including nail biting and diplopia) (Including Parkinsonism and antipsychotic-induced dyskinesia), hypertension, dyslipidemia, nonalcoholic fatty liver disease, hyperlipidemia, hyperlipidemia, hyperlipidemia, hypercholesterolemia, Obesity-related kidney diseases, and methods for the prevention and treatment of sleep apnea are also provided. In some embodiments, there is provided a method of treating tobacco smoking in an individual attempting to reduce the frequency of cigarette smoking, comprising administering a compound herein, optionally in combination with a supplement, and a compound herein, optionally in combination with a supplement. / RTI >; Assist in stopping or reducing the use of tobacco products in an individual attempting to stop or reduce the use of tobacco products; Assist smoking cessation and associated weight gain prevention; Controlling weight gain associated with smoking cessation by an individual attempting to stop cigarette smoking; Reducing weight gain associated with smoking cessation by an individual attempting to stop cigarette smoking; Treating nicotine dependence, addiction and / or withdrawal in an individual who attempts to treat nicotine dependence, addiction and / or withdrawal; Methods are also provided for reducing the likelihood of recurring use of nicotine by an individual attempting to stop using nicotine.일부 실시양태에서 본원에서의 화합물이 제공된다. 일부 실시양태에서 체중 관리, 포만감 유도, 및 식품 섭취 감소, 및 비만, 항정신병제-유발 체중 증가, 제2형 당뇨병, 프레더-윌리 증후군, 담배/니코틴 의존, 약물 중독, 알콜 중독, 병적 도
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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