ANTIBODY-PHARMACEUTICAL CONJUGATES (ADC) BINDING TO 191P4D12 PROTEINS

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专利权人:

Agensys; Inc.;Agensys, Inc.;Seattle Genetics, Inc.

发明人:

SATPAEV, Daulet,MORRISON, Robert, Kendall,MORRISON, Karen Jane, Meyrick,GUDAS, Jean,JAKOBOVITS, Aya,TORGOV, Michael,AN, Zili

申请号：

DK11831345

公开号：

DK2621526T3

申请日:

2011.09.29

申请国别(地区):

DK

年份:

2018

代理人:

摘要：

The present disclosure relates to antibody drug conjugates (ADC's) with auristatin E that binds to 191P4D12 protein and variants thereof. 191P4D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in some cancers. The ADC's of provide a therapeutic composition for the treatment of cancer.

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