MACDONALD, GREGOR, JAMES,THURING, JOHANNES, WILHELMUS, JOHN F.,STANISLAWSKI, PAULINE, CAROL,ZHUANG, WEI,VAN ROOSBROECK, YVES, EMIEL, MARIA,VAN DEN KEYBUS, FRANS, ALFONS, MARIA
申请号：
MYPI 2010003974
公开号：
MY152486A
申请日:
2009.03.18
申请国别(地区):
MY
年份:
2014
代理人:
摘要：
THE PRESENT INVENTION RELATES TO 1-ARYL-3-ANILINE-5-ALKYL-1,2,4-TRIAZOLE DERIVATIVES AND ANALOGUES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESSES FOR PREPARING THEM, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY, ACCORDING TO FORMULA (I). THE INVENTION PARTICULARLY RELATES TO POTENT POSITIVE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS, SUCH POSITIVE ALLOSTERIC MODULATOR HAVING THE CAPABILITY TO INCREASE THE EFFICACY OF NICOTINIC RECEPTOR AGONISTS. (NO SUITABLE FIGURE)
