James MADDEN,David James HALLETT,Alastair PARKES,Ali RAOOF,Xiaolu WANG
申请号:
US14073981
公开号:
US20140073627A1
申请日:
2013.11.07
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to compounds of formula (I)wherein R1, R1a, R1b, R2, R3 and X, X1, X2, X3 have the meaning as cited in the description and the claims. Said compounds are useful as Bradykinin B1 antagonists. The invention also relates to pharmaceutical compositions, the preparation of such compounds as well as the production and use as medicament.