HENWOOD GERALDINE ANNE,MACK RANDALL JEROME,SHARR CHRISTOPHER THOMAS,KOLENG JOHN JOSEPH
申请号：
NZ59697610
公开号：
NZ596976A
申请日:
2010.05.17
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
596976 The disclosure relates to a method of treating or preventing pain in a non-human mammal without significant sedation, said method comprising administering to a non-human mammal across oral mucosa thereof a dosage of dexmedetomidine or a pharmaceutically acceptable salt thereof (such as dexmedetomidine hydrochloride) in a range between about 0.05 &mu；g per kg body weight and about 1.50 &mu；g per kg body weight, wherein said dexmedetomidine or a pharmaceutically acceptable salt thereof is in a pharmaceutically acceptable vehicle (such as liquid water) for administration to an oral mucosa of the non-human mammal. Also disclosed are compositons for use in the method and dosage forms thereof. Forms of pain that may be treated with the methods include: idiopathic pain, neuralgia pain, myalgia pain, hyperalgia pain, hyperpathia pain, neuritis pain, neuropathic pain, pain associated with or caused by cancer, pain associated with or caused by viral infection, pain associated with or caused by physical trauma, pain associated with or caused by arthritis, headache pain, lower back pain, pain associated with or caused by surgery, pain associated with or caused by burn, or pain associated with or caused by blunt force trauma.
