BURKE, PATRICK J.,JEFFREY, SCOTT,HAMILTON, JOSEPH Z.
申请号：
CA2959424
公开号：
CA2959424A1
申请日:
2015.09.10
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Compounds and compositions are disclosed in which a quaternized drug unit is linked to a targeting ligand unit from which a tertiary amine-containing drug is released at the targeted site of action. Methods for treating diseases characterized by the targeted abnormal cells, such as cancer or an autoimmune disease using the compounds and compositions of the invention are also disclosed.
