A catheter insertion device includes a housing, a needle, a catheter, and a guide wire. The needle has a proximal end positioned in the housing and a distal end extending beyond a distal end of the housing in a first position. The catheter is positioned coaxially over the needle, and may include a flexible tube and a catheter hub on a proximal end of the flexible tube. A proximal portion of the flexible tube and the catheter hub may be positioned in the housing. The guidewire may have a proximal end positioned in the housing and a distal end positioned in a lumen of the needle. The catheter insertion device also may include a handle coupled to the catheter, wherein movement of the handle relative to the housing moves the catheter hub from a position in the housing to a position outside of the housing.