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METHOD FOR PREDICTION OF RISK OF FORMATION OF EROSION-ULCER LESIONS OF GASTRODUODENAL ZONE IN PATIENTS WITH ARTERIAL HYPERTENSION
专利权人:
federalnoe gosudarstvennoe byudzhetnoe obrazovatelnoe uchrezhdenie vysshego obrazovaniya "Permskij gosudarstvennyj meditsinskij universitet imeni akademika E.A. Vagnera" Ministerstva zdravookhraneniya
发明人:
Malyutina Natalya Nikolaevna (RU),Малютина Наталья Николаевна (RU),Luzina Svetlana Vladimirovna (RU),Лузина Светлана Владимировна (RU),Sheludko Valerij Stepanovich (RU),Шелудько Валерий Степанович (RU
申请号:
RU2020109295
公开号:
RU0002727688C1
申请日:
2020.03.02
申请国别(地区):
RU
年份:
2020
代理人:
摘要:
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to internal diseases, gastroenterology, cardiology and clinical laboratory diagnostics, and can be used for prediction of risk of formation of erosion-ulcer lesions of gastroduodenal zone in patients with arterial hypertension (AH) by laboratory blood analysis. Patient with AH in blood is examined for thrombocyte count, leukocyte count, glucose concentration, cholesterol level, content of monocyte chemotactic protein-1 and endothelin-1. Predicted risk of formation of erosion-ulcer lesions of the gastroduodenal zone is calculated by formula: Y=0.515+0.001⋅X1+0.547⋅X2-0.002⋅X3+0.044⋅X4-0.107⋅X5-0.048⋅X6, where Y – predicted risk of formation of erosive-ulcerous gastroduodenal lesions in patients with AH, X1 – concentration of monocyte chemotactic protein-1 (pg/ml), X2 – level of endothelin-1 (fmole/ml), X3 – amount of thrombocytes (109/l), X4 – number of leukocytes (109/l), X5 – concentration of glucose (mmol/l), X6 is cholesterol concentration (mmol/l). If Y is equal to or greater than 1, a risk of formation of erosion-ulcerous gastroduodenal lesions in the patients with AH is predicted. If Y is less than 1, there is no risk of formation of erosion-ulcerous gastroduodenal lesions in AH patients.EFFECT: method provides the possibility of increasing the prediction accuracy of the risk of formation of erosion-ulcerous gastroduodenal lesions in the patients with arterial hypertension by using a quantitative prediction criterion based on laboratory blood test results.1 cl, 3 exИзобретение относится к медицине, а именно к внутренним болезням, гастроэнтерологии, кардиологии и клинической лабораторной диагностике, и может быть использовано для прогнозирования риска формирования эрозивно-язвенных поражений гастродуоденальной зоны у пациентов с артериальной гипертензией (АГ) с помощью лабораторного анализа крови. У пациента с АГ в крови определяют количество тромбоцитов, лейкоцитов, концентрацию глюкозы, уровень
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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