Natural treatment or regeneration cell therapy can be promoted non-invasively in daily life. A knee joint model was constructed by three-dimensional analysis of measurement data obtained by measuring the outer shape and internal space shape of the knee joint of the subject, and based on the knee joint model, aimed at improvement of the symptoms of the knee joint. The transition state in the correction direction is continuously or stepwise simulated, and based on the transition state, an exoskeleton mold capable of continuously or stepwise finely adjusting the knee joint in the correction direction is designed based on the transition state.日常生活において非侵襲に自然治療又は再生細胞治療の促進を行うことができる。対象者の膝関節部の外郭形状及び内部空間形状を測定して得られる測定データを3次元解析して膝関節モデルを構築し、膝関節モデルを基準として、膝関節部の症状改善に向けた矯正方向への遷移状態を連続的又は段階的にシミュレーションし、遷移状態に基づいて、膝関節部を矯正方向へ連続的又は段階的に微調整可能な外骨格モールドを設計する。