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Novel condensed pyridine or condensed pyrimidine derivative, and medicinal agent comprising same
专利权人:
KOWA CO.; LTD.
发明人:
MORIMOTO, TOSHIHARU,森元俊晴,森元俊晴,KOSHIZAWA, TOMOAKI,越泽智章,越澤智章,WATANABE, GEN,渡部玄,渡部玄,OHGIYA, TADAAKI,扇谷忠明,扇谷忠明,YAMASAKI, NAO,山崎奈穗,山崎奈穗,INOUE, NORIYUKI,井上训之,井上訓之
申请号:
TW100121559
公开号:
TW201204733A
申请日:
2011.06.21
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
Disclosed is a novel compound which has an activity of promoting the secretion of insulin from a pancreatic ss cell and is useful as a prophylactic and/or therapeutic agent for diseases associated with hyperglycemia, such as diabetes. Specifically disclosed is a compound represented by general formula (1) [wherein one of A and B represents a nitrogen atom and the other represents a nitrogen atom or CR10 X represents an oxygen atom, a sulfur atom or -(CH2)n-N(R12)- Y represents an oxygen atom, a sulfur atom or -N(R13)- and R1 to R9 independently represent a hydrogen atom or another substituent], a salt thereof, or a solvate of the compound or the salt.本發明係提供具有促進由胰臟β細胞分泌胰島素之作用,且可用於作為起因於高血糖之疾病,例如糖尿病之預防及/或治療劑的新穎化合物。下列一般式(1)所示之化合物或其鹽、或其溶劑化物[式中,A及B中之一者表示氮原子,另一者表示氮原子或CR10,X表示氧原子、硫原子或-(CH2)n-N(R12),Y表示氧原子、硫原子或-N(R13)-,R1~R9表示氫原子、其他之取代基]。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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